Thursday, July 07, 2005

Pharma Companies Researching Female Orgasms

The first arousal drugs aimed at women's gray matter are expected to be on the market in the next couple of years. The active ingredient: testosterone, a "male" hormone that is also naturally present in women's bodies in smaller quantities. Procter & Gamble plans to release a testosterone patch, Intrinsa, and Illinois-based BioSante is entering Phase III clinical trials with its testosterone formulation, LibiGel. Even so, most researchers agree that testosterone isn't the end of the story. Testosterone drugs will never have a direct, rapid effect on women the way Viagra does on men, because it's a hormone that fosters an overall sense of strength and well-being rather than specifically catalyzing sexual arousal. More promising is a drug called PT-141, which is being developed by Palatin Technologies in New Jersey. The first in a new class of drugs called melanocortin agonists, PT-141 targets the central nervous system. Early trials show both genital arousal and increased sexual desire in women who take it. But even more precisely targeted drugs are coming - those that won't light up the entire nervous system in the blind hope of hitting pleasure buttons, but actually home in on parts of the brain that are directly connected to arousal and orgasm.

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