A gene that partly explains people's different susceptibility to HIV has been identified by US scientists. The discovery may help doctors tailor treatment to patients' genetic make-up.
Researchers know that certain people are naturally resistant to HIV. Some people develop full-blown AIDS several months after infection by the virus, whereas others remain disease-free for decades.
Differences in a gene called CCL3L1 may underlie some of this resistance, say Sunil Ahuja of the University of Texas Health Science Center, San Antonio, and his colleagues. They report in Science that individuals carrying extra copies of this gene are less likely to contract HIV or to progress to full-blown AIDS1.
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